Maintaining a healthy gut microbiome is crucial for overall health as it can play a vital role in digestion, immune function, and even mental well-being. The good news is that our diet may have a huge impact on the structure, composition and functioning of the gut microbiome.
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What is the Gut Microbiome and why is it so important to our health?
The gut microbiome refers to the complex community of microorganisms, including bacteria, viruses and fungi, importantly the gastrointestinal tract (GI) has been found to harbour a complex and dynamic population of them. The gut microbiome is vital to health for several reasons, encompassing a wide range of physiological functions and influencing numerous aspects of both physical and mental well-being. Here's a breakdown of why the gut microbiome is so important to our body and health (7):
- Digestive Health
- Nutrient Breakdown and Absorption: The gut microbiome helps digest complex carbohydrates, fibres, and certain proteins that the human digestive system alone cannot process. This breakdown produces short-chain fatty acids and other beneficial metabolites that are crucial for gut health.
- Vitamin Production: Certain gut bacteria synthesise essential vitamins such as B vitamins (B12, riboflavin, and folate) and vitamin K, which are necessary for various bodily functions, including blood coagulation and energy metabolism (8).
- Immune System Regulation
- Immune Development: The gut microbiome plays a fundamental role in the development and maturation of the immune system. It helps in training the immune system to distinguish between harmful pathogens and benign antigens, reducing the risk of autoimmune diseases (9).
- Protection Against Pathogens: By maintaining a balanced microbial environment, the gut microbiome helps prevent colonization by pathogenic microbes through competitive inhibition and production of antimicrobial substances.
- Metabolic Functions
- Energy Harvesting: Gut bacteria aid in extracting energy from food, influencing caloric intake and energy storage, which can impact body weight and metabolism (10).
- Mental Health and Neurological Functions
- Gut-Brain Axis: The gut microbiome communicates with the brain through the gut-brain axis, involving neural, hormonal, and immune pathways. This interaction can influence mood, stress response, and cognitive functions (11).
- Protection Against Chronic Diseases
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Obesity and Metabolic Syndrome: An imbalanced microbiome (dysbiosis) can contribute to obesity and related metabolic disorders by affecting fat storage, insulin sensitivity, and energy regulation.
- Cardiovascular Health: Certain microbial metabolites, such as trimethylamine N-oxide (TMAO), are linked to cardiovascular diseases. Conversely, beneficial metabolites can protect against heart disease by reducing inflammation and supporting blood vessel health (12).
Top Gut-Microbiome nutrients:
Consuming a diverse and fiber-rich diet, including fruits, vegetables, whole grains, and fermented foods, promotes a healthy microbiome. Avoiding excessive intake of processed foods, sugars, and unhealthy fats is also beneficial. Here are some top nutrients that are beneficial for the gut:
- Fiber (1)
Insoluble Fiber:
- Sources: Whole grains, nuts, seeds, and vegetables.
- Benefits: Adds bulk to stool and helps food pass through the digestive tract.
Soluble Fiber (2):
- Sources: Oats, legumes, apples, and citrus fruits.
- Benefits: Forms a gel-like substance in the gut, promoting healthy digestion and feeding beneficial bacteria.
- Prebiotics (3):
- Definition: Non-digestible food components that promote the growth of beneficial microorganisms in the intestines.
- Sources: Garlic, onions, leeks, asparagus, bananas, and Jerusalem artichokes.
- Benefits: Serve as food for probiotics (beneficial bacteria), promoting a healthy microbiome.
- Probiotics (4):
- Definition: Live beneficial bacteria that can be consumed through fermented foods or supplements.
- Sources: Yogurt, kefir, sauerkraut, kimchi, miso, and kombucha.
- Benefits: Enhance the diversity and population of beneficial gut bacteria.
- Polyphenols (5):
- Definition: Micronutrients with antioxidant properties.
- Sources: Berries, green tea, red wine (in moderation), dark chocolate, and olives.
- Benefits: Have prebiotic-like effects, promoting the growth of beneficial bacteria.
- Omega-3 Fatty Acids (6):
- Sources: Fatty fish (salmon, mackerel, sardines), flaxseeds, chia seeds, and walnuts.
- Benefits: Help reduce inflammation and promote a healthy balance of gut bacteria.
Sources
- Guan, Z. W., Yu, E. Z., & Feng, Q. (2021). Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota.Molecules (Basel, Switzerland), 26(22), 6802. https://doi.org/10.3390/molecules26226802
- Guan, Z. W., Yu, E. Z., & Feng, Q. (2021). Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota.Molecules (Basel, Switzerland), 26(22), 6802. https://doi.org/10.3390/molecules26226802
- Oniszczuk, A., Oniszczuk, T., Gancarz, M., & Szymańska, J. (2021). Role of Gut Microbiota, Probiotics and Prebiotics in the Cardiovascular Diseases.Molecules (Basel, Switzerland), 26(4), 1172. https://doi.org/10.3390/molecules26041172
- Wang, X., Zhang, P., & Zhang, X. (2021). Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity.Molecules (Basel, Switzerland), 26(19), 6076. https://doi.org/10.3390/molecules26196076
- Wang, X., Qi, Y., & Zheng, H. (2022). Dietary Polyphenol, Gut Microbiota, and Health Benefits.Antioxidants (Basel, Switzerland), 11(6), 1212. https://doi.org/10.3390/antiox11061212
- Costantini, L., Molinari, R., Farinon, B., & Merendino, N. (2017). Impact of Omega-3 Fatty Acids on the Gut Microbiota.International journal of molecular sciences, 18(12), 2645. https://doi.org/10.3390/ijms18122645
- Thursby, E., & Juge, N. (2017). Introduction to the human gut microbiota.The Biochemical journal,474(11), 1823–1836. https://doi.org/10.1042/BCJ20160510
- Uebanso, T., Shimohata, T., Mawatari, K., & Takahashi, A. (2020). Functional Roles of B-Vitamins in the Gut and Gut Microbiome.Molecular nutrition & food research, 64(18), e2000426. https://doi.org/10.1002/mnfr.202000426
- Liu, Y., Wang, J., & Wu, C. (2022). Modulation of Gut Microbiota and Immune System by Probiotics, Pre-biotics, and Post-biotics.Frontiers in nutrition, 8, 634897. https://doi.org/10.3389/fnut.2021.634897
- Noor, J., Chaudhry, A., Batool, S., Noor, R., & Fatima, G. (2023). Exploring the Impact of the Gut Microbiome on Obesity and Weight Loss: A Review Article.Cureus, 15(6), e40948. https://doi.org/10.7759/cureus.40948
- Mayer, E. A., Nance, K., & Chen, S. (2022). The Gut-Brain Axis.Annual review of medicine, 73, 439–453. https://doi.org/10.1146/annurev-med-042320-014032
- Tang, W. H., Kitai, T., & Hazen, S. L. (2017). Gut Microbiota in Cardiovascular Health and Disease.Circulation research, 120(7), 1183–1196. https://doi.org/10.1161/CIRCRESAHA.117.309715